DI-87 Ligand-Linker Conjugates 2 N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

and show dose dependent potentiation of VEGF or bFGF induced cell proliferation

3-dimethylbutanamido]propanamido}ethyl)disulfanyl]ethyl}carbamoyl)ethyl]-2

TAME was used at 50-200 µM final concentration in various in vitro assays

DI-87 Ligand-Linker Conjugates 2 N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTACDI 87 is an orally active and selective deoxycytidine kinase (dCK) inhibitor with an EC50 of 10. 2 nM. DI 87 has antitumor activity and is used in combination therapy against tumors expressing dCK. Product information CAS Number: 2107280 55 5 Molecular Weight: 502. 65 Formula: C23H30N6O3S2 Chemical Name: 2 {[(1R) 1 (2 {4 methoxy 3 [2 (morpholin 4 yl)ethoxy]phenyl} 5 methyl 1,3 thiazol 4 yl)ethyl]sulfanyl}pyrimidine 4,6 diamine Smiles: