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(1999) Nat
In cellular assays ML141 inhibited Cdc42-related filopodia formation and cell migration
1380288-87-8
memory consolidation is inherently limited by the ISR
ADC Toxin Monomethyl auristatin E (MMAE) - CAS# 474645-27-7 60023 (1999) NatMonomethyl auristatin E (MMAE, vedotin), CAS No. 474645 27 7, is a very potent anti mitotic agent that inhibits cell division by blocking the polymerisation of tubulin. Because of ts super toxicity, it cannot be used as a drug itself. In recent cancer therapy developments, it is linked to a monoclonal antibody (mAb) that recognizes a pecific marker expression in cancer cells and directs MMAE to the cancer cells. The linker linking MMAE to the
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