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11aS)-1-hydroxy-11a-methyl-1-(prop-2-en-1-yl)-1H
a metabolite of vitamin D3 with intestinal calcium transport activity
macranthoidin A
Blankley CJ
Damnacanthal Size:Contact [email protected] for quotation 11aS)-1-hydroxy-11a-methyl-1-(prop-2-en-1-yl)-1HDamnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 lck autophosphorylation and phosphorylation of exogenous substrates with IC50s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti inflammatory effects in
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