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InChi: InChI=1S/C20H28FN7/c1-5-13(3)24-19-12(2)8-23-20(26-19)25-17-7-14(9-22-18(17)21)28-11-15-6-16(28)10-27(15)4/h7-9
Etoposide phosphate disodium (0-1 μM
Yamashita Y
InChiKey: QNYRAEKLMNDRFY-UHFFFAOYSA-N
RO2959 hydrochloride(x) - CAS# 1219927-22-6 Catalog No.:M12941-2 InChi: InChI=1S/C20H28FN7/c1-5-13(3)24-19-12(2)8-23-20(26-19)25-17-7-14(9-22-18(17)21)28-11-15-6-16(28)10-27(15)4/h7-9RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1 Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL 2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. Product information CAS Number: 1219927 22 6 Molecular
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