EGFR-IN-2 H 032 amide-alkylC5-acid 47(3):291-300

47(3):291-300

is a p53 pathway activator

57(8):3205-12

Bortezomib treatment leads to PARP cleavage in a time-dependent manner with concentrations as low as 100 nM being effective at 24 hr

EGFR-IN-2 H 032 amide-alkylC5-acid 47(3):291-300EGFR IN 2 is a a noncovalent, irreversible, mutant selective second generation EGFR inhibitor. Product information CAS Number: 1643497 70 4 Molecular Weight: 551. 66 Formula: C26H33N9O3S Chemical Name: 2 (1 {1 [(2S) butan 2 yl] 6 ({2 [1 (cyclopropanesulfonyl) 1H pyrazol 4 yl]pyrimidin 4 yl}amino) 1H pyrazolo[4,3 c]pyridin 3 yl}azetidin 3 yl)propan 2 ol Smiles: C[C@@H](CC)N1N=C(C2=CN=C(C=C12)NC1C=CN=C(N=1)C1=CN(N=C1)S(=O)(=O)C1CC1)N1CC(C1)C(C)(C)O