Ki8751 (5 mg/kg) completely inhibits tumor growth without affecting body weight
3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoyl]oxy}ethoxy)ethyl]carbamoyl}methoxy)imino]-2
with an average cytostatic IC50 of >60 microM in 15 cell types
Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway
CM 11 suvastatin D6 Sodium Ki8751 (5 mg/kg) completely inhibitsCM11, also known as Homo PROTAC, acts as a potent VHL inhibitor and induces complete depletion of pVHL30. Product information CAS Number: 2244684 49 7 Molecular Weight: 1179. 45 Formula: C58H82N8O14S2 Synonym: Homo PROTAC Homo PROTAC pVHL30 degrader 1 CM11 VHL inhibitor Chemical Name: N1, N20 Bis((S) 1 ((2S, 4R) 4 hydroxy 2 ((4 (4 methylthiazol 5 yl)benzyl)carbamoyl)pyrrolidin 1 yl) 3, 3 dimethyl 1 oxobutan 2 yl) 3, 6, 9, 12, 15, 18