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InChiKey: HUUPKFUYSQNNLO-FAESNJTISA-N
used for treatment of cardiovascular diseases
193(7):3278-87
8'-bichromen]-4-one
NB-360 Size:Contact [email protected] for quotation InChiKey: HUUPKFUYSQNNLO-FAESNJTISA-NNB 360 is a potent, brain penetrable, and orally bioavailable dual BACE1 BACE2 inhibitor (IC50: mouse and human BACE1=5 nM; BACE2=6 nM). NB 360 shows a superior pharmacological profile and robust reduction of amyloid and neuroinflammation in amyloid precursor protein(APP) transgenic mice. NB 360 can completely block the progression of A deposition in the brains of APP transgenic mice. NB 360 shows excellent selectivity over the related aspartyl
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