MK-4101 Size:Contact [email protected] for quotation Smiles: OC1C=C2OC(=CC2=CC=1)C1C=C(O)C=C(O)C=1

Smiles: OC1C=C2OC(=CC2=CC=1)C1C=C(O)C=C(O)C=1

31(5):845-52

(±)-α-Lipoic acid

InChiKey: RNSLRQNDXRSASX-UHFFFAOYSA-N

MK-4101 Size:Contact [email protected] for quotation Smiles: OC1C=C2OC(=CC2=CC=1)C1C=C(O)C=C(O)C=1MK 4101 is a Smoothened (SMO) antagonist (IC50 of 1. 1 M for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1. 5 M for mouse cells; IC50 of 1 M for KYSE180 oesophageal cancer cells). MK 4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis. Product information CAS Number: 935273 79 3 Molecular Weight: 493. 47 Formula: C24H24F5N5O Chemical Name: 5 (3,3 difluorocyclobutyl) 3