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An ERRbeta/gamma agonist modulates GRalpha expression
3-diphenyl-2-sulfanylidene-1
a hydroxamate-based
PubMed PMID: 24698779
ML241 Size:Contact [email protected] for quotation An ERRbeta/gamma agonist modulates GRalphaIC50: 100 nM ML241 is identified as a potent and selective inhibitors of p97 ATPase. The p97 AAA (ATPase associated with diverse cellular activities), also called VCP (valosin containing protein), is an critical therapeutic target for cancer and neurodegenerative diseases. p97 plays important roles in a broad array of cellular processes, such as degradation of misfolded membrane and secretory proteins, homotypic fusion of endoplasmic reticulum and
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