6-(4-Methoxyphenyl)-3-pyridazinamine 19400 Momelotinib inhibits PI3K/AKT and Ras/MAPK

Momelotinib inhibits PI3K/AKT and Ras/MAPK signaling induced by IL-6 and IGF-1

CAS Number: 1446113-23-0

25)16-10-14(19)17-13(7-5-9-20-17)18(16)21(22)23/h3-11H

InChi: InChI=1S/C26H46O12S/c1-25-3-5-26(6-4-25)39(27

6-(4-Methoxyphenyl)-3-pyridazinamine 19400 Momelotinib inhibits PI3K/AKT and Ras/MAPK6 (4 Methoxyphenyl) 3 pyridazinamine is a GABAA receptor antagonist. Ionotropic GABAA receptors are ligand gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. In vitro: 6 (4 Methoxyphenyl) 3 pyridazinamine is an intermediate in the synthesis of SR 95103 [2 (3 carboxypropyl)