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The IC50 of NSC745885 is 0
Chemical Name: (2E)-N-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide
Smiles: N[C@H](CO)C1C=C(C=CC=1)C1=CC(COC2=CC=CC=C2CC(O)=O)=CC=C1
CAS Number: 883986-34-3
SAICAR Size:Contact [email protected] for quotation The IC50 of NSC745885 isSAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme selective manner, with an EC50 of 0. 3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose limited conditions. Product information CAS Number: 3031 95 6 Molecular Weight: 454. 28 Formula: C13H19N4O12P Chemical Name: (2S) 2 ({5 amino 1 [(2R,3R,4S,5R) 3,4 dihydroxy 5 [(phosphonooxy)methyl]oxolan 2 yl] 1H
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