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5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants
Smiles: CO/N=C/[C@H]1[C@H]2CC[C@@H](C[C@@H]1C1C=CC(Cl)=C(Cl)C=1)N2C
RA190 stabilized targets of human papillomavirus (HPV) E6 oncoprotein
34(5):2095-104
IM-12 - CAS# 1129669-05-1 Size:Solid 10 mg 5-diaryl-2-aminopyridine ALK2 inhibitors reveals unalteredIM 12 is a cell permeable indolylmaleimide that acts as a GSK 3 inhibitor. IM 12 is potent and selective enhances canonical Wnt signalling. IM 12 inhibits GSK 3 activity and subsequently increases catenin concentration significantly in hNPCs. When used to treat human neural progenitor cells, IM 12 promoted neuronal differentiation resulting in an increase of neuronal cells. Product information CAS Number: 1129669 05 1 Molecular Weight: 377. 41