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HIF-C2 provides an opportunity to delineate differences in HIF-1 and HIF-2 biology and serves as an entry point for development of HIF-2 inhibitor drugs for treating diseases
an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity
17(4):641-51
CAS Number: 869296-13-9
Cyclovirobuxine D - CAS# 860-79-7 Catalog No.:M12537-10 HIF-C2 provides an opportunity toCyclovirobuxine D (CVB D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria mediated apoptosis. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction.
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