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5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4
Additional PK studies of Zuranolone in dog show low clearance (<10% of hepatic blood flow)
2018 Dec 15
also known as Thalidomide 4'-ether-alkylC4-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry
BGB-102 - CAS# 807640-87-5 biletin (Hexamethoxyflavone) 5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4BGB 102 is a potent multi kinase inhibitor against EGFR, HER2, and HER4 with IC50s of 9. 6 nM, 18 nM and 40. 3 nM, respectively. Product information CAS Number: 807640 87 5 Molecular Weight: 457. 36 Formula: C22H25BrN4O2 Chemical Name: 5 bromo 18 methoxy 10 methyl 16 oxa 2,10,21,23 tetraazatetracyclo[15. 6. 2. 0,. 0,]pentacosa 1(24),3,5,7,17(25),18,20,22 octaene Smiles: COC1=CC2=NC=NC3NC4=CC(Br)=CC=C4CN(C)CCCCCOC1=CC2=3 InChiKey: JXDYOSVKVSQGJM
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