C16-PAF famerazine Sodium Salt EX-527 was used at 1-10

EX-527 was used at 1-10 µM in vitro and in cellular assays

2016 Aug 17

InChi: InChI=1S/C34H36FN5O2/c1-3-38(4-2)34(42)32(25-11-6-5-7-12-25)40-21-19-39(20-22-40)31-17-16-27(23-30(31)35)37-33(41)29-15-9-8-14-28(29)26-13-10-18-36-24-26/h5-18

5ClH/c32-9-12-42-19-15-24(30(40)38-28-17-26(43-13-10-33)20-5-1-3-7-22(20)36-28)35-25(16-19)31(41)39-29-18-27(44-14-11-34)21-6-2-4-8-23(21)37-29

C16-PAF famerazine Sodium Salt EX-527 was used at 1-10C16 PAF (PAF (C16)), a phospholipid mediator, is a platelet activating factor and ligand for PAF G protein coupled receptor (PAFR). C16 PAF exhibits anti apoptotic effect and inhibits caspase dependent death by activating the PAFR. C16 PAF is a potent MAPK and MEK ERK activator. C16 PAF induces increased vascular permeability. Product information CAS Number: 74389 68 7 Molecular Weight: 523. 68 Formula: C26H54NO7P Synonym: PAF (C16) Chemical Name: (R)