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PubMed Central PMCID: PMC4786772
Smiles: CC1OC(=O)OC=1COC(=O)C1=C(N=C(CCC)N1CC1C=CC(=CC=1)C1=CC=CC=C1C1NN=NN=1)C(C)(C)O
InChi: InChI=1S/C33H42O12/c1-16-21(42-17(2)34)14-33(40)28(44-29(39)20-11-9-8-10-12-20)26-31(7
Formula: C27H31FN4O2
MK-3697 p-016 PubMed Central PMCID: PMC4786772MK 3697 is a highly potent, orally bioavailable selective orexin 2 receptor antagonists . MK 3697 is also the third insomnia drug, currently being developed by Merck. MK 3697 has Ki = 0. 95 nM. Orexin receptor antagonists have demonstrated clinical utility for the treatment of insomnia. In vivo tests results on MK 3697 demonstrated improved stability and TDI profiles as well as excellent sleep efficacy across species. Product information CAS Number:
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