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DK419 inhibited Wnt/β-catenin signaling
making it an allosteric antagonist
BAY 36-7620 did not disrupt sensorimotor gating
CAS Number: 1081110-72-6
Pristinamycin 21278 DK419 inhibited Wnt/β-catenin signalingPristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic resistant pathogens, particularly Gram positive bacteria, including Methicillin resistant Staphylococcus aureus (MRSA), Vancomycin resistant S. aureus (VRSA) and Enterococcus faecium (VREF).
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