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RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 CAS Number: 1380548-02-6

SKU: 95108891985

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Description

CAS Number: 1380548-02-6

Swearingen D

9-dicarboxamide

It inhibits KDM2A at IC50 ~1

RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 CAS Number: 1380548-02-6RX 3117, also known as TV 1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX 3117 is taken up by cells through a carrier mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX DP) and triphosphate forms (RX TP). The triphosphate form is incorporated into

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