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UNC2281 inhibits steady-state Mer kinase phosphorylation with an IC50 value of 22 nM
KB-R7943 mesylate blocks NMDAR-mediated ion currents
These actions of Mibefradil are consistent with K+ channel inhibition
including both SET-domain-containing and non-SET domain-containing methyltransferases
A-317491 sodium salt hydrate thalin UNC2281 inhibits steady-state Mer kinaseA 317491 sodium salt hydrate is a non nucleotide P2X3 and P2X2 3 receptor antagonist, which inhibits calcium flux mediated by the receptors. IC50 value: Target: P2X2 3 receptor It is known that P2X3 and P2X2 3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer
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